BOTOX® Cosmetic is a simple, nonsurgical, physician-administered treatment that can temporarily smooth moderate to severe frown lines between the brows in people from 18 to 65 years of age. It is the only treatment of its type approved by the Food and Drug Administration (FDA). One 10-minute treatment—a few tiny injections—and within days there's a noticeable improvement in moderate to severe frown lines between the brows, which can last up to 4 months. Results may vary. BOTOX® Cosmetic is a purified protein produced by the Clostridium botulinum bacterium, which reduces the activity of the muscles that cause those frown lines between the brows to form over time. In 2005, almost 3.3 million procedures were performed with FDA-approved BOTOX® Cosmetic. There’s only one BOTOX® Cosmetic.
What is Botox?
Botox® is a trade name for botulinum toxin A. In this way, Botox® is related to botulism. Botulism is a form of food poisoning that occurs when someone eats something containing a neurotoxin produced by the bacterium Clostridium botulinum. Botulinum toxin A is one of the neurotoxins produced by Clostridium botulinum. The most serious symptom of botulism is paralysis, which in some cases has proven to be fatal. The botulinum toxins (there are seven -- types are A through G) attach themselves to nerve endings. Once this happens, acetylcholine, the neurotransmitter responsible for triggering muscle contractions, cannot be released. A series of proteins, VAMP, syntaxin and SNAP-25, are essential for the release of acetylcholine. Certain botulinum toxins attack these proteins. Botulinum toxin A (Botox) affects the SNAP-25. Basically, the botulinum toxins block the signals that would normally tell your muscles to contract. Say, for example, it attacks the muscles in your chest -- this could have a profound impact on your breathing. When people die from botulism, this is often the cause -- the respiratory muscles are paralyzed so it’s impossible to breathe.
Botox is a drug made from a toxin produced by the bacterium Clostridium botulinum. It's the same toxin that causes a life-threatening type of food poisoning called botulism. Doctors use it in small doses to treat health problems, including
1. Temporary removal of facial wrinkles
2. Severe underarm sweating
3. Cervical dystonia - a neurological disorder that causes severe neck and shoulder muscle contractions
4. Blepharospasm - uncontrollable blinking
5. Strabismus - misaligned eyes
Botox injections work by weakening or paralyzing certain muscles or by blocking certain nerves. The effects last about three to four months.
Side effects can include
1. Pain at the injection site
2. flu-like symptoms
3. Headache and upset stomach.
Injections in the face may also cause temporary drooping eyelids. You should not use Botox if you are pregnant or breast feeding.
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